AACR Call to Action To improve our nation’s health, including the lives of patients with cancer, and sustain our leadership in cancer science and medicine, AACR urges Congress to prioritize funding medical research by providing the following appropriations in FY 2024: Cancer Inequities in the United States HIGHER cancer death rates From 2018 to 2020: • Black women had 1.4 times and two times higher death rates for breast and uterine cancer, respectively, compared to White women, despite having similar incidence rates. • American Indian and Alaska Native men had 1.8-, 2.1-, and 2.7-times higher death rates due to cancers of the kidney, liver, and stomach, respectively, compared to White men. • Hispanic men and women had twofold higher death rates for stomach cancer, compared to White men and women. 2-FOLD or higher Compared to cisgender patients, transgender patients have twofold or higher increased risk of death from non-Hodgkin lymphoma, prostate cancer, and bladder cancer. 78% higher Among older adults with newly diagnosed cancer, rural residents have a 78 percent higher one-year mortality compared to urban residents. Screening for Early Detection In May 2023, USPSTF issued a draft recommendation for breast cancer screening: Researchers estimate that the revised recommendation could save 19 percent more lives from breast cancer. 50 years 40 years DRAFT PREVIOUS CANCER TYPE NIH NCI CDC's Division of Cancer Prevention and Control FDA's Oncology Center of Excellence $50.924 BILLION $9.988 BILLION $472.4 MILLION $50 MILLION New Frontiers in Cancer Science and Medicine Researchers are hopeful that advances in discovery science, and technologies that enable it, will lead to a future where the success of treating all cancers is higher, and where the likelihood of a cure is possible. Single-cell genomics to understand molecular changes in every cell of the tumor Artificial Intelligence to aid in cancer detection and diagnosis. Microbiome modulation to improve treatment responsiveness. Liquid biopsy to detect multiple cancer types from a single test. Cancer vaccines to personalize treatment for each patient. AACR Cancer Progress Report 2023 11
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