Appendix Surgeries for the Prevention of Cancer GENETIC MUTATION CANCER TECHNIQUE REMOVES APC Colon cancer Colectomy Colon/large intestine BRCA1 or BRCA2 Breast and ovarian cancers Mastectomy and salpingooophorectomy Breasts, and ovaries and fallopian tubes CDH1 Breast and stomach cancers Mastectomy and gastrectomy Breast and stomach Mutations associated with Lynch syndrome Colon, endometrial, and ovarian cancers Colectomy, hysterectomy, and salpingo-oophorectomy Colon/large intestine, uterus, and ovaries and fallopian tubes RET Medullary thyroid cancer Thyroidectomy Thyroid SUPPLEMENTAL TABLE 1 Appendix AACR Cancer Progress Report 2023 191
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