AACR Cancer Report 2023

Estimated Incidence and Mortality* for Selected Cancers ESTIMATED 2023 INCIDENCE ESTIMATED 2023 DEATHS Total Male Female Total Male Female All Sites 1,958,310 1,010,310 948,000 609,820 322,080 287,740 Head and Thorax Region Breast 300,590 2800 297,790 43,700 530 43,170 Tongue 18,040 13,180 4860 2940 1950 990 Mouth 14,820 8680 6140 3090 1870 1220 Pharynx 20,070 16,340 3730 4140 3260 880 Other oral cavity 1610 1090 520 1410 1060 350 Larynx 12,380 9900 2480 3820 3070 750 Lung and bronchus 238,340 117,550 120,790 127,070 67,160 59,910 Eye and orbit 3490 1900 1590 430 240 190 Brain and other nervous system 24,810 14,280 10,530 18,990 11,020 7970 Gastrointestinal (GI) System Esophagus 21,560 17,030 4530 16,120 12,920 3200 Stomach 26,500 15,930 10,570 11,130 6690 4440 Small intestine 12,070 6580 5490 2070 1170 900 Colon & rectum 153,020 81,860 71,160 52,550 28,470 24,080 Anus, anal canal, & anorectum 9760 3180 6580 1870 860 1010 Liver and intrahepatic bile duct 41,210 27,980 13,230 29,380 19,000 10,380 Gallbladder and other biliary 12,220 5750 6470 4510 1900 2610 Pancreas 64,050 33,130 30,920 50,550 26,620 23,930 Skin (excluding basal and squamous) Melanoma of the skin 97,610 58,120 39,490 7990 5420 2570 Other nonepithelial skin 7320 4690 2630 4480 3060 1420 Urogenital System Uterine cervix 13,960 - 13,960 4310 - 4310 Uterine corpus 66,200 - 66,200 13,030 - 13,030 Ovary 19,710 - 19,710 13,270 - 13,270 Vulva 6470 - 6470 1670 - 1670 Vagina and other genital organs, female 8470 - 8470 1740 - 1740 Prostate 288,300 288,300 - 34,700 34,700 - Testis 9190 9190 - 470 470 - Penis and other genital organs, male 2050 2050 - 470 470 - Urinary bladder 82,290 62,420 19,870 16,710 12,160 4550 Kidney and renal pelvis 81,800 52,360 29,440 14,890 9920 4970 Ureter and other urinary organs 4470 2810 1660 990 600 390 Endocrine System Thyroid 43,720 12,540 31,180 2120 970 1150 Hematologic System Acute lymphocytic leukemia 6540 3660 2880 1390 700 690 Chronic lymphocytic leukemia 18,740 12,130 6610 4490 2830 1660 Acute myeloid leukemia 20,380 11,410 8970 11,310 6440 4870 Chronic myeloid leukemia 8930 5190 3740 1310 780 530 Hodgkin lymphoma 8830 4850 3980 900 540 360 Non-Hodgkin lymphoma 80,550 44,880 35,670 20,180 11,780 8400 Myeloma 35,730 19,860 15,870 12,590 7000 5590 Other leukemia 5020 3280 1740 5210 3150 2060 Other Cancers Bones and joints 3970 2160 1810 2140 1200 940 Soft tissue (including heart) 13,400 7400 6000 5140 2720 2420 *Rounded to the nearest 10. Source: Estimated new cases are based on 2005-2019 incidence rates reported by the North American Association of Central Cancer Registries (NAACCR). Estimated deaths are based on 2006-2020 U.S. mortality data, National Center for Health Statistics, Centers for Disease Control and Prevention. Table is modified from (28). TABLE 1 AACR Cancer Progress Report 2023 Cancer in 2023 16

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